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Pakistan’s federal health ministry has moved to reassure the public that the country faces minimal threat from plague following the unexplained death of a young laboratory worker in Russia that has triggered international health concerns and precautionary quarantines.

Speaking to media outlets, a senior ministry official confirmed that Pakistan’s risk level remains “very low” despite uncertainty surrounding the October 2 death of Darya Shipilova, a 28-year-old researcher at the Irkutsk Anti-Plague Research Institute in Siberia.

The ministry has nonetheless activated Border Health Services at all entry points across Pakistan and confirmed that the National Institute of Health possesses full diagnostic capability for plague detection should any suspected cases emerge.

“The Ministry of Health and NIH are fully aware of the situation and monitoring developments closely,” the director general of health stated, adding that even the World Health Organisation lacks complete information about the Russian case.

Shipilova’s death from severe pneumonia of unknown origin initially prompted Russian authorities to quarantine approximately 200 individuals who had contact with her. Wild speculation erupted on social media, with unverified theories suggesting she dropped a test tube containing live bacteria, contracted illness during foreign travel, or fell sick near the Mongolian border.

Russian health officials have firmly rejected these narratives. Nearly 5,000 laboratory tests have been conducted, and 90 percent of quarantined individuals have since been released with no plague detected among them. Authorities insist Shipilova was vaccinated against the dangerous pathogens she handled and that no relevant disease agents were found in her contacts.

Russia’s health regulator declared Wednesday there is no epidemic risk and began winding down precautionary measures. However, the cause of the pneumonia that killed Shipilova remains officially unexplained, fueling continued international concern.

The WHO has formally requested additional information from Moscow under International Health Regulations, which require countries to respond within 24 hours to potential cross-border health threats. WHO Director-General Tedros Adhanom Ghebreyesus emphasized that “timely, complete and transparent information sharing” is essential to assess actual public health risks.

The global health body also revealed it is investigating reports of a second institute employee suffering pneumonia of undetermined cause, further complicating the picture.

Neighboring countries have responded with heightened vigilance. Kazakhstan, Kyrgyzstan, and Uzbekistan have strengthened border health measures, while the United States has urged Russia to share accurate information quickly. President Donald Trump stated Wednesday that Washington does not believe the death involved a bioweapon, addressing social media speculation.

Plague, caused by the bacterium Yersinia pestis, circulates primarily among small animals and fleas. It can spread to humans through infected flea bites, inhalation of infectious particles, or rarely through ingestion. The disease carries a 30 to 100 percent mortality rate if untreated but responds well to antibiotics when caught early.

The Irkutsk institute was established in 1934 specifically to control plague outbreaks across Siberia, Mongolia, and China. Plague remains endemic to the region, though human cases in Russia are extremely rare.

The WHO’s current risk assessment rates the threat as moderate to low for the Irkutsk region, low for Russia overall, and very low for Europe and beyond.

For Pakistan, health authorities stress that robust surveillance systems and diagnostic infrastructure are in place. The country’s proactive response reflects lessons learned from previous global health emergencies, including COVID-19, where early border monitoring proved crucial in managing imported cases.

While the mystery surrounding Shipilova’s death continues, Pakistani health officials maintain that current evidence suggests no immediate danger to the country’s population.